Overview of Diclofenac Sodium Powder
Diclofenac sodium (chemical formula C14H10Cl2NNaO2, molecular weight 318.13) is a potent non-steroidal anti-inflammatory drug (NSAID) known for its significant analgesic, anti-inflammatory, and antipyretic properties. Its mechanism of action involves suppressing prostaglandin synthesis, which in turn mediates pain and inflammation. As a result, Diclofenac sodium stands as a prominent NSAID agent, widely applied in the management of mild to moderate acute and chronic pain conditions in orthopedic practice, including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Specifications – Diclofenac Sodium Powder
| Product name | Diclofenac sodium | |
| Appearance | White or slightly yellowish, slightly hygroscopic, crystalline powder | Conforms |
| Solubility | Sparingly soluble in water, freely soluble in methanol, soluble in ethanol, slightly soluble in acetone | Conforms |
| Identification | A. IR | Conforms |
| B. TLC | Conforms | |
| C. Tests of sodium salt | Conforms | |
| Appearance of solution | The solution is clear | Conforms |
| UV 440nm≤0.05 | 0.015 | |
| Related substances(HPLC) | Impurity A ≤0.2% | Not detected |
| Impurity F ≤0.15% | ≤0.05% | |
| Any individual impurity ≤0.1% | 0.02% | |
| Total impurities ≤0.4% | 0.07% | |
| pH value | 7.0-8.5 | 7.3 |
| Melt point | About 280℃, with decomposition | Conforms |
| Heavy metals | ≤10ppm | Conforms |
| Loss on drying | ≤0.5% | 0.20% |
| Assay | 99.0~101.0% | 99.70% |
Functionality of Diclofenac Sodium Powder
Diclofenac sodium is an NSAID recognized for its potent anti-inflammatory, pain-relieving, and fever-reducing effects. It exerts its pharmacological actions by selectively inhibiting cyclooxygenase enzymes, thereby blocking prostaglandin production. Its analgesic and anti-inflammatory potency surpasses indomethacin by 2–2.5 times and acetylsalicylic acid by 26–50 times. Key attributes include a strong therapeutic profile, minimal side effects, low dosage requirements, and low inter-patient variability.
Applications of Diclofenac Sodium Powder
- Joint disorders: Managing pain and inflammation in rheumatoid arthritis, osteoarthritis, spondyloarthropathies, gouty arthritis, and other chronic joint conditions.
- Soft tissue rheumatic pain: Alleviating symptoms such as shoulder syndrome, tenosynovitis, bursitis, myalgia, and post-exercise pain.
- Acute mild-to-moderate pain: Treating postoperative pain, post-injury pain, muscle strain, primary dysmenorrhea, dental pain, and headaches.
Shipping & Delivery Information
Our professional logistics team ensures reliable and timely delivery of orders. Packages can be shipped via express or DDP (Delivered Duty Paid) service, depending on your needs.
Frequently Asked Questions
Q1. Can I request a sample of Diclofenac sodium before purchasing?
Yes, we provide 50–100g complimentary trial samples for quality evaluation.
Q2. What is the process for placing an order?
Once we confirm your request, a proforma invoice with detailed payment instructions will be issued for your review.
Q3. What after-sales support do you offer?
We support express and DDP shipping methods. For express deliveries, we continuously monitor your shipment and assist with customs clearance. In the unlikely event of a quality concern, we will promptly work toward a resolution.
Q4. How long does delivery take?
Ex-stock items are shipped within three days of confirmed payment.
Q5. Do you offer volume-based discounts?
Yes, larger order quantities qualify for increased discounts. For a tailored quote, please reach out to our team.
Our broader portfolio includes additional pharmaceutical-grade raw materials. For inquiries, please contact us at the email below:
Email: [email protected]
