Desflurane

Introduction of Desflurane

Desflurane (also known by its English name: Desflurane), or desflurane for short, is a halogenated ether anesthetic primarily used to sustain anesthesia. Similar to other halogenated ether anesthetics, it is administered as a racemic mixture. In modern clinical settings, desflurane and sevoflurane are increasingly supplanting isoflurane as preferred inhalational anesthetics. Owing to its low blood solubility, desflurane demonstrates the most rapid induction and recovery among all volatile anesthetics, with drug effects wearing off swiftly. However, it has certain limitations, including relatively lower anesthetic potency, a sharp, irritating smell, and a high production cost. In regions with limited healthcare budgets, this has hindered widespread adoption. That said, in low-flow anesthesia techniques, the cost gap between desflurane and isoflurane becomes nearly negligible [1]. At vapor concentrations above 10%, desflurane may induce elevated heart rate and provoke airway reactivity, which is why it is rarely used for anesthetic induction.

Synonym

DIFLUOROMETHYL1,2,2,2-TETRAFLUOROETHYLETHER; DESFLURANE; 1,2,2,2-TETRAFLUOROETHYLDIFLUOROMETHYLETHER; (2S)-2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane; Difluoromethyl1,2,2,2-tetrafluoroethylether 99%; Difluoromethyl1,2,2,2-tetrafluoroethylether 99%; i653; Suprane

Product Specification

Function

Desflurane exhibits high volatility yet remains in liquid form at room temperature. Anesthesia delivery systems designed for desflurane typically incorporate a dedicated heating unit to maintain a stable temperature, minimizing fluctuations in vapor concentration caused by ambient conditions. It is well-documented that desflurane—along with enflurane and, to a lesser extent, isoflurane—can chemically react with carbon dioxide absorbents commonly used in anesthesia circuits, resulting in decomposition and the production of trace yet measurable levels of carbon monoxide. Conditions such as absorbent desiccation or use in high-insufflation settings can significantly amplify this reaction, particularly when Baralyme is used as the absorbent, leading to increased CO generation.

Application

Primarily utilized in surgical anesthesia for the maintenance of general anesthesia.

Packaging & Delivery

Standard packaging is 25kg per drum. For orders exceeding 50kg, air freight is available; for quantities above 100kg, shipment via sea freight is provided.

FAQ

1. Can I receive a free sample?
   
   Yes, Extract Makers provides complimentary desflurane samples to qualified clients; however, the customer is responsible for all shipping and handling charges.

   
   

2. What payment methods are accepted and what are the terms?
   
   Payments may be processed via T/T (Telegraphic Transfer), Credit Card, Western Union, PayPal, and various other secure channels.

   
   

3. How does Extract Makers ensure product quality?
   
   With over a decade of experience in the industry, Extract Makers maintains a robust quality assurance system, complemented by a final product verification prior to shipment, ensuring reliability and consistency.

   
   

4. Do you offer OEM services?
   
   Yes, Extract Makers supports OEM manufacturing. Please submit your specifications, and we will provide a customized quote along with sample production for your review.

   
   

5. How can I contact you?
   
   You can reach us via email, WhatsApp, or through a direct phone call. All contact information is available on our website.

   
   

We are capable of supplying a wide range of active pharmaceutical ingredients (APIs) to meet customer demands. For any inquiries or additional information about our products, please feel free to contact us via email: [email protected]

Sarah