What is Azelaic Acid?
Azelaic acid represents a specialized pharmaceutical compound primarily employed for managing skin conditions including acne, melasma, and cutaneous hyperpigmentation. Additionally, this versatile substance serves as a crucial building block in organic synthesis. Within industrial sectors, it contributes to the production of plasticizers utilized across polymer, elastomer, and related material applications. The compound also plays a role in manufacturing specialized lubricants for aerospace applications and capacitor production. Contemporary manufacturing processes typically employ unsaturated fatty acids like oleic acid alongside corresponding triglycerides derived from castor or cottonseed oil as precursors for azelaic acid synthesis.
Alternative Designations
azelaicacid,technicalgrade;Azelainic acid;Emerox 1110;Emerox 1144;emerox1110;emerox1144;Emery's L-110;ninandioic acid
Product Specifications
| Product Name: | Azelaic acid | CAS NO.: | 123-99-9 |
| Molecular weight: | 188.22 | EINECS: | 204-669-1 |
| Formula: | C9H16O4 | Density: | 1,029 g/cm3 |
Therapeutic Properties
Azelaic acid demonstrates antimicrobial activity against both anaerobic and aerobic skin-dwelling microorganisms. Clinical investigations reveal that consistent topical application of azelaic acid formulations for 2-3 months results in substantial reduction of cutaneous bacterial populations, particularly within hair follicle environments, confirming its direct bactericidal capabilities. Moreover, topical administration modifies the lipid composition present on skin surfaces, decreasing free fatty acid content. The compound exhibits anti-keratinization properties when applied to both healthy and acne-affected skin, working by inhibiting filamentous keratin synthesis and consequently reducing follicular hyperkeratosis. Azelaic acid targets dysregulated melanocytes selectively, suppressing their heightened activity. Extended topical treatment consequently reduces melanin production in patients exhibiting age-related hyperpigmentation, though it does not affect normally pigmented skin. The substance also displays antiproliferative and cytotoxic properties through disruption of mitochondrial respiratory function and cellular DNA synthesis pathways.
Utilization Areas
Primary applications of azelaic acid center around dioctyl azelate (DOZ) plasticizer production, with additional usage as precursor material for fragrances, lubricants, industrial oils, and polyamide polymer synthesis. DOZ enhances cold-weather performance, flexibility, reduced volatility, and durability in cable insulation, film applications, synthetic leather, and similar products. This plasticizer also functions as a softening agent for synthetic rubber formulations. Japanese manufacturers utilizing azelaic acid for DOZ production consume approximately 70% of global azelaic acid supply. Azelaic acid undergoes ammonia dehydration to form azelonitrile intermediate products.
The compound serves as a valuable reagent and organic synthesis starting material. Its versatility extends to pharmaceutical and personal care product manufacturing, with applications in dermatological treatments for pigmentation disorders including melasma, benign nevi, malignant melanoma, and solar lentigines. The substance demonstrates significant efficacy against common acne vulgaris and shows therapeutic benefit for rosacea and seborrheic dermatitis management.
Packaging & Delivery
| Cargo weight | Packing | Shipping method | Lead-time |
| 5-50kg | Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum | International express | 7-10days |
| 100-200kg | 25kg/drum,use two layer PP bag,then into cardboard drum | Air shipping | 7-10days |
| Over 500kg | 25kg/drum,use two layer PP bag,then into cardboard drum | Sea shipping | 20-45days |
Common Questions
Sample Availability
Affirmative - we provide complimentary azelaic acid samples, though recipients cover shipping expenses.Payment Conditions
Acceptable payment methods include T/T bank transfers, credit card transactions, Western Union transfers, PayPal, and alternative digital payment platforms.Quality Assurance Measures
Our organization maintains approximately ten years of specialized industry expertise with established quality control protocols. Pre-shipment comprehensive testing ensures defect-free product delivery.Custom Manufacturing Services
We accommodate custom manufacturing requirements and private labeling arrangements.Contact Information
Communication available via email, WhatsApp messaging, direct telephone contact, or website inquiry forms. Complete contact directory accessible through our online platform.
We maintain extensive inventory of pharmaceutical and cosmetic raw materials. For inquiries or additional product information, please contact us via email: [email protected] [[email protected]]
