Atorvastatin Powder

What is Atorvastatin?

Atorvastatin is a pharmaceutical compound primarily used to manage cholesterol levels and support cardiovascular health. It functions as a selective inhibitor of HMG-CoA reductase, an enzyme critical in cholesterol production in the liver. By blocking this enzyme, atorvastatin effectively lowers levels of LDL ("bad") cholesterol, total cholesterol, triglycerides, and apolipoprotein B—proteins integral to cholesterol transport.

Simultaneously, atorvastatin helps elevate HDL ("good") cholesterol, which aids in removing excess cholesterol from the bloodstream. These combined effects are essential in slowing or reversing atherosclerosis—the buildup of plaque in arteries—which significantly lowers the risk of major cardiovascular events such as heart attack, stroke, and peripheral artery disease.

Storage and Transportation:

For bulk quantities, store in a tightly sealed, airtight container in a cool, dry environment, away from direct light and moisture. Proper storage ensures stability and maintains pharmacological potency during transit and handling.

Application:

Indications:

1. Hypercholesterolemia and Mixed Dyslipidemia:
   Useful in patients with primary hypercholesterolemia, including heterozygous familial hypercholesterolemia or combined lipid disorders (classified under Fredrickson Types IIa and IIb). This product is indicated when dietary control and non-pharmacological interventions fail to achieve target lipid levels. Atorvastatin effectively reduces LDL cholesterol, total cholesterol, apolipoprotein B, and triglycerides.

In homozygous familial hypercholesterolemia, atorvastatin may be used alone or in combination with advanced lipid-lowering treatments—such as LDL apheresis—to lower total and LDL cholesterol when alternative options are limited.

2. Coronary Heart Disease (CHD):
   For individuals diagnosed with CHD—or those at high risk due to conditions like diabetes or symptomatic atherosclerosis—alongside hypercholesterolemia or mixed lipid abnormalities, atorvastatin provides significant benefits, including:

• Reduced risk of non-fatal myocardial infarction
• Lower rates of fatal and non-fatal strokes
• Decreased need for revascularization procedures
• Reduced hospitalizations from congestive heart failure
• Lower incidence of angina pectoris

Dosage and Administration:

• The standard adult dosage ranges from 10 mg to 80 mg once daily, typically administered in the evening with or after a meal.
• Treatment often begins at 10 mg once daily, with fasting lipid profiles checked within the first 4 weeks. Dose adjustments should be based on clinical response.
• Maximum recommended daily dose is 80 mg.
• Available tablet strengths: 10 mg, 20 mg, and 40 mg.
• Avoid consuming grapefruit or grapefruit juice due to the risk of serious drug interactions that may amplify side effects.
• Discontinuation of atorvastatin should only occur under medical supervision, as continuous use may be necessary for effective long-term cholesterol management.

Delivery & Shipping:

Packaging:
Powder form: Securely packed in vacuum-sealed, light-resistant aluminum foil to preserve integrity and prevent oxidation.

Why Choose Extract Makers?

With over eight years of expertise in supplying and researching pharmaceutical-grade raw materials, plant-derived extracts, and healthcare ingredients, Extract Makers stands as a trusted partner for clients across China, the United States, Europe, the Middle East, Southeast Asia, and beyond.

Our core values—Health, Innovation, Dedication, and Exceptional Service—guide every aspect of our operations. We are committed to delivering high-purity compounds with reliable sourcing, stringent quality controls, and responsive customer support.

For inquiries and orders, contact us at: [email protected]

Sarah