Product Introduction:
Pepsinogen is produced by the chief cells of the gastric fundus and converted into active pepsin at a pH range of 1.5 to 5.0. It breaks down proteins into peptides, with partial conversion into amino acids like tyrosine and phenylalanine. Measuring pepsin levels in gastric juice helps differentiate between hypochlorhydria (low acid with potential normal pepsin) and achlorhydria (deficiency in both acid and pepsin). Gastric hypoacidity is often linked to significant mucosal damage, such as in pernicious anemia, where pepsin secretion may be impaired—a key diagnostic clue. Pepsin output is frequently reduced in chronic gastritis, gastric dilation, and cholangitis. High gastric acid diseases like duodenal ulcers typically exhibit increased pepsin activity. First identified in 1836 by Theodor Schwann during digestion research, pepsin is the initial animal-derived enzyme discovered and the sole stomach proteolytic enzyme. Its optimal pH is 1–2, primarily cleaving peptide bonds involving aromatic or acidic amino acids. Synthesized in gastric glands, it is secreted as zymogen granules and activated by gastric hydrochloric acid. Medicinal-grade pepsin, extracted from porcine stomach, aids indigestion but is contraindicated for peptic ulcers.
Storage & Transportation:
For large-scale handling, store in a cool, dry, sealed container.
Applications:
Essential for gastric protein digestion, pepsin is a proteolytic enzyme enhancing nutrient assimilation, pathogen control, and toxin neutralization. While the body produces it naturally, commercial supplements can further support these functions.
Key Benefits of Pepsin:
- Degrades indigestible proteins
- Alleviates indigestion and intestinal permeability
- Promotes bile secretion
- Assists hepatic detoxification
- Enhances nutrient uptake
- Mitigates malnutrition risks
- Counteracts enzyme inhibitors in egg whites, nuts, seeds, grains, and legumes
- Eliminates gastric pathogenic bacteria
- Liberates vitamin B12 from food proteins for bioavailability
Delivery & Shipping:
Express Options:
- FedEx, DHL, USPS, TNT, UPS: Within 7–10 days (no weight limit; door-to-door)
- EMS: 10–15 days (no limit)
- ePacket/NL Post: ~30 days (under 2kg)
Packaging:
Powder: Vacuum-sealed aluminum foil
Why Choose Us?
Extract Makers is a premier manufacturer and innovator of pharmaceutical raw materials, plant-derived extracts, and nutraceutical ingredients with over 8 years of industry expertise. Our client network spans China, the U.S., Europe, the Middle East, Southeast Asia, and beyond.
Our philosophy centers on Vitality, Dedication, and Client-Centric Service.
We uphold "Premium Quality, Client Priority" as our core commitment.
For inquiries on bulk pepsin powder, contact us at [email protected].
