Unlock Respiratory Relief with Fevipiprant Powder
Product Overview:
Discover Fevipiprant Powder, also identified as NVP-QAW039 or QAW039, a pioneering compound in respiratory care. This potent, orally active antagonist targets the CRTh2 receptor, presenting a significant advancement in the management of asthma. Its remarkable affinity for the human CRTh2 receptor (1.14 ± 0.44 nM), showcased in Chinese hamster ovary cells, underscores its targeted action. Fevipiprant exhibits competitive and reversible binding with the natural agonist, prostaglandin D2 (PGD2), and effectively inhibits PGD2-induced cytokine release in human Th2 cells. This compound has demonstrated a notable capacity to reduce eosinophilic airway inflammation and is well-tolerated in patients grappling with persistent moderate-to-severe asthma, even those with elevated sputum eosinophil counts recalcitrant to inhaled corticosteroid treatment. Furthermore, Fevipiprant boasts a favorable safety profile, making it a promising option for therapeutic intervention.
Detailed Specifications:
- Product Name: Fevipiprant Powder
- Appearance: Pristine White Powder
- Purity: 99%
- Analytical Method: High-Performance Liquid Chromatography (HPLC)
- CAS Number: 872365-14-5
- Molecular Formula: C19H17F3N2O4S
- Molecular Weight: 179.22 g/mol
- Solubility Profile: Readily soluble in ethanol, chloroform, propylene glycol, and ethylenediamine. Exhibits slight solubility in diethyl ether and partial solubility in water.
- Grades Available: Exceeds 99% purity (NLT 99%), Food Grade, Pharmaceutical Grade.
- Production Capacity: 1000 kg per month
- Origin: Synthetically derived
- Packaging: Tailored to client specifications
- Minimum Order Quantity (MOQ): 1 kg
- Storage Recommendations: Preserve in a cool, dry environment, shielded from intense light and heat.
Visual Representation:
Therapeutic Advantages of Fevipiprant:
Initially explored for its potential in hair loss treatment, Fevipiprant's primary therapeutic focus has shifted towards its robust efficacy in respiratory diseases, particularly asthma. Its ability to reduce eosinophilic airway inflammation is a cornerstone of its benefit profile, offering significant relief to patients with persistent moderate-to-severe asthma who experience elevated sputum eosinophil counts despite standard inhaled corticosteroid regimens. The consistent demonstration of a favorable safety profile further enhances its appeal as a viable treatment option.
Storage and Shipment Logistics:
For bulk quantities, store in a cool, dry, and hermetically sealed container to maintain product integrity.
Delivery & Shipping Options:
We offer a variety of efficient shipping channels to meet your needs:
| Express Service | Quantity | Estimated Shipping Time | Service Feature |
|---|---|---|---|
| Fedex | Any | 7 to 10 days | Door-to-Door |
| EMS | Any | 10 to 15 days | Door-to-Door |
| Epacket/NL post | Under 2kg | Approximately 30 days | Door-to-Door |
| DHL/USPS/TNT/UPS | Any | 7 to 15 days | Door-to-Door |
*Specific carrier availability may vary by region.
Packaging:
- Powder: Securely vacuum-sealed foil packing for optimal preservation.
Why Partner with Us?
As a premier supplier and research leader in pharmaceutical raw materials, natural plant extracts, and health supplement ingredients, we bring over eight years of unparalleled expertise to the industry. Our extensive network of collaborations spans across China, the USA, Europe, the Middle East, Southeast Asia, and other global regions.
Our guiding principles are rooted in fostering Health, Youth, Passion, and Service.
We adhere firmly to the philosophy of "Top Quality, Customer First" in every facet of our operations.
For inquiries regarding Fevipiprant Powder, please reach out to [email protected].
