Setipiprant Powder: An Introduction
Setipiprant was initially synthesized by Actelion as an antagonist targeting the prostaglandin D2 receptor. Compelling research has since demonstrated that, in individuals experiencing male pattern baldness, the concentration of PGD2 is significantly elevated in areas affected by hair loss compared to unaffected regions. Therapeutic intervention aimed at blocking the binding of PGD2 to its receptor holds considerable promise for stimulating hair growth. Setipiprant fulfills this role, underpinned by a strong foundation of positive clinical trials.
Chemical Information:
- Name: Setipiprant
- Flash Point: 371.4±31.5 °C
- PSA: 62.54
- Chemical Formula: C24H19FN2O3
- LogP: 3.39
- Molecular Weight: 402.418
- Vapor Pressure: 0.0±2.3 mmHg at 25°C
- CAS No.: 866460-33-5
- Refractive Index: 1.682
- Boiling Point: 690.4±55.0 °C at 760 mmHg
- Density: 1.4±0.1 g/cm3
Setipiprant Powder Specifications:
| Attribute | Specification | Result |
|---|---|---|
| Product Name | Setipiprant | |
| CAS No. | 866460-33-5 | Conforms |
| Description | White to light yellow powder | Conforms |
| Identification | H-NMR | Positive |
| Assay (HPLC at 230nm) | ≥98.0% | 99.75% |
Functions of Setipiprant Powder:
Setipiprant is an orally bioavailable, highly selective CRTH2 antagonist. Its efficacy in addressing androgenetic alopecia has been demonstrated, and preliminary data suggest a favorable safety profile.
Related Products:
Fevipiprant, Finasteride, Dutasteride, RU58841, CB-03-01, WAY 316606, Minoxidil, Ketoconazole
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