Product Introduction:
Dihydromyricetin (DMY), also referred to as ampelopsin, is a flavanonol— a structurally distinct subgroup of flavonoids. Sourced and refined by Extract Makers, dihydromyricetin is extracted and purified from the leaves of Vine Tea (Teng Cha), a rare and distinctive tea variety native to China. The botanical source is Ampelopsis grossedentata, a climbing plant traditionally valued in herbal medicine. Vine Tea is naturally abundant in bioactive compounds including flavonoids, amino acids, vitamins, and essential micronutrients, with dihydromyricetin being its most prominent constituent. Historically used in traditional Chinese medicine, Vine Tea supports heat clearance, dampness regulation, liver protection, blood circulation enhancement, and qi balance.
Specification:
Product Name: Dihydromyricetin
Synonyms: Ampelopsin, DHM, Ampeloptin
CAS No.: 27200-12-0
Botanical Origin: Ampelopsis grossedentata / Vine Tea
Plant Part Used: Stems and Leaves
Molecular Formula & Weight: C15H12O8, 320.25 g/mol
Extraction Solvents: Ethanol and water
Available Grades: Dihydromyricetin 50%, 80%, 90%, 98% (HPLC)
Appearance: Light yellow to off-white crystalline powder
Solubility: Solubility in water at 25°C is 4%; fully dissolves in boiling water; miscible in acidified water, ethanol, and acetone; very poorly soluble in ethyl acetate.
Certificate of Analysis (COA):
Product Name: Vine Tea Extract
Plant Part: Leaf
Botanical Name: Ampelopsis grossedentata
Country of Origin: China
Extraction Solvent: Ethanol & Water
| ITEM | SPECIFICATION | STANDARD / METHOD |
| Appearance | Off white to Yellow white Powder | Visual |
| Odor & Taste | Little bitter and Characteristic flavor | Sensory |
| Loss on drying | ≤5.0% | 2g/105ºC/5hrs |
| Ash | ≤5.0% | 2g/800ºC/5hrs |
| Particle size | 95% pass 80 mesh | Sieve |
| Heavy metals | ≤10ppm | Colorimetric method |
| Lead (Pb) | ≤2ppm | Atomic Absorption |
| Arsenic (As) | ≤2ppm | Atomic Absorption |
| Cadmium(Cd) | ≤1ppm | Atomic Absorption |
| Mercury(Hg) | ≤0.1ppm | Atomic Absorption |
| Solvent residue | ≤5000ppm | GC |
| Dihydromyricetin | ≥98.0% | HPLC |
| Total Plate count | ≤1000CFU/g | ChP |
| Yeast & Mould | ≤100CFU/g | ChP |
| Escherichia Coli | Negative | ChP |
| Salmonella | Negative | ChP |
| Packing | Pack in paper-drums and two food grade poly bags inside. Net weight: 15~20kg/drum | |
| Storage condition | Store in a well closed place with constant low temperature and no direct sun light | |
| Shelf life | Two years when properly stored. | |
Packaging: Packed in paper drums with two inner food-grade polyethylene liners. Net weight: 15–20 kg per drum.
Storage Conditions: Keep in a tightly sealed, cool, dry environment, protected from direct sunlight.
Shelf Life: 24 months if stored as directed.
Applications of Dihydromyricetin / Ampelopsin / Ampeloptin:
1) Liver protection and hangover support: Aids in mitigating alcohol-induced liver stress. Recommended dosage range for hangover relief: 1–8 mg/kg body weight, based on 80% DHM.
2) Free radical scavenging
3) Antioxidant activity
4) Anti-inflammatory effects
5) Antimicrobial action against fungi and bacteria
6) Inhibition of thrombus (blood clot) formation
7) Anticancer properties: Under active investigation for efficacy against leukemia and nasopharyngeal carcinoma (NPC).
8) Animal feed additive: Functions as a natural antioxidant; helps control E. coli, aflatoxins, and mold contamination in feed.
9) Meat quality enhancement: Contributes to improved flavor and palatability in poultry products.
Functions and Applications of Vine Tea Extract
1) Free radical neutralization and antioxidant protection:
Vine tea extract efficiently suppresses lipid peroxidation in biological systems. It shields endogenous antioxidant enzymes from free radical-induced damage, thereby strengthening the body’s overall resistance to oxidative stress.
2) Antibacterial and antifungal activity:
The extract exhibits potent growth inhibition against Staphylococcus aureus and Bacillus subtilis, and shows suppressive effects on mycotoxigenic molds such as Aspergillus flavus, Aspergillus niger, Penicillium, and Alternaria. Dihydromyricetin specifically inhibits Staphylococcus aureus (including drug-resistant strains) as well as Pseudomonas aeruginosa.
3) Liver-protective mechanisms:
Dihydromyricetin significantly attenuates elevated serum levels of ALT and AST—key indicators of hepatocellular injury. It also reduces total bilirubin, demonstrating strong efficacy in lowering aminotransferases and alleviating jaundice. Studies in rodent models confirm that the extract inhibits liver fibrosis progression.
4) Hypoglycemic and lipid-lowering effects:
Dihydromyricetin lowers blood lipid concentrations in mice, reduces hepatic cell damage associated with hyperlipidemia, and enhances antioxidant defense. It simultaneously assists in regulating elevated blood glucose levels.
5) Anti-inflammatory properties:
The extract reliably reduces xylene-induced ear swelling in mice and inhibits acetic acid-induced pain responses (writhing), demonstrating robust anti-edematous and analgesic activities.
6) Antitumor potential:
Vine tea extract exhibits concentration-dependent inhibition of proliferation in multiple tumor cell lines, highlighting its role in emerging oncological research.
Delivery & Packaging
Standard packaging includes 1 kg foil-lined pouches or 25 kg export-grade drums, with double food-grade plastic liners. For specialized requirements, Extract Makers offers fully customizable packaging solutions upon request.
Shipments can be arranged via courier, sea freight, or air cargo, depending on urgency, volume, and destination. For detailed packaging visuals and logistics options, refer to the accompanying images.
For further inquiries or technical questions about Dihydromyricetin (Ampelopsin) powder, please contact us at:
[email protected]
